FGF23

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
FGF23 ADHR, FGFN, HPDR2, HYPF, PHPTC fibroblast growth factor 23 pdf NONE NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). No expression in human and no homolog found.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome2 1 2 1 2 2 0 7 1
Read_Max
batR. aegyptiacusTranscriptome 5 2 3 3 3 2 NA 4 3
Read_Max
bat_genomeR. aegyptiacusGenome 9 4 4 5 3 2 4 8 6
DESeq
humanH. sapiensGenome 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0
DESeq
batR. aegyptiacusTranscriptome 12.76 3.72 4.66 3.75 7.57 4.85 1.0 5.13 5.37
DESeq
bat_genomeR. aegyptiacusGenome 56.72 32.86 49.09 19.75 30.14 40.47 20.24 32.51 27.4

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 1.0 1.0 0.0 0.0 0.0
7h 1.0 1.0 1.0 0.0 0.0 0.0
23h 1.0 1.0 1.0 0.0 0.0 0.0

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 1.0 1.0 0.0 0.0 0.0
Ebov 1.0 1.0 1.0 0.0 0.0 0.0
Marv 1.0 1.0 1.0 0.0 0.0 0.0

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 12.76 3.75 1.0 -1.77 -3.67 -1.91
7h 3.72 7.57 5.13 1.02 0.46 -0.56
23h 4.66 4.85 5.37 0.06 0.2 0.15

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 12.76 3.72 4.66 -1.78 -1.45 0.33
Ebov 3.75 7.57 4.85 1.01 0.37 -0.64
Marv 1.0 5.13 5.37 2.36 2.42 0.07