ITGA1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ITGA1 VLA-1, CD49 Antigen-Like Family Member A,VLA1, CD49a integrin, alpha 1 NM_181501 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens integrin, alpha 1 (ITGA1), mRNA. This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008].

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome330 292 219 250 350 187 349 386 143
Read_Max
batR. aegyptiacusTranscriptome 68 61 36 76 50 35 51 64 56
Read_Max
bat_genomeR. aegyptiacusGenome 193 203 112 195 116 84 110 264 217
DESeq
humanH. sapiensGenome 6483.46 5779.6 5408.92 5931.41 6080.25 3663.21 5871.25 5287.1 4630.92
DESeq
batR. aegyptiacusTranscriptome 1074.7 967.69 550.69 1162.98 869.41 542.5 1041.1 966.84 694.64
DESeq
bat_genomeR. aegyptiacusGenome 3227.87 3167.02 2301.85 2995.04 3070.48 2337.99 3252.15 2947.38 2630.22

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 6483.46 5931.41 5871.25 -0.13 -0.14 -0.01
7h 5779.6 6080.25 5287.1 0.07 -0.13 -0.2
23h 5408.92 3663.21 4630.92 -0.56 -0.22 0.34

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 6483.46 5779.6 5408.92 -0.17 -0.26 -0.1
Ebov 5931.41 6080.25 3663.21 0.04 -0.7 -0.73
Marv 5871.25 5287.1 4630.92 -0.15 -0.34 -0.19

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1074.7 1162.98 1041.1 0.11 -0.05 -0.16
7h 967.69 869.41 966.84 -0.15 -0.0 0.15
23h 550.69 542.5 694.64 -0.02 0.34 0.36

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1074.7 967.69 550.69 -0.15 -0.96 -0.81
Ebov 1162.98 869.41 542.5 -0.42 -1.1 -0.68
Marv 1041.1 966.84 694.64 -0.11 -0.58 -0.48