ITGA1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
ITGA1	VLA-1, CD49 Antigen-Like Family Member A,VLA1, CD49a	integrin, alpha 1	NM_181501	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens integrin, alpha 1 (ITGA1), mRNA. This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008].

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	330	292	219	250	350	187	349	386	143
Read_Max	R. aegyptiacus	Transcriptome	68	61	36	76	50	35	51	64	56
Read_Max	R. aegyptiacus	Genome	193	203	112	195	116	84	110	264	217
DESeq	H. sapiens	Genome	6483.46	5779.6	5408.92	5931.41	6080.25	3663.21	5871.25	5287.1	4630.92
DESeq	R. aegyptiacus	Transcriptome	1074.7	967.69	550.69	1162.98	869.41	542.5	1041.1	966.84	694.64
DESeq	R. aegyptiacus	Genome	3227.87	3167.02	2301.85	2995.04	3070.48	2337.99	3252.15	2947.38	2630.22

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	6483.46	5931.41	5871.25	-0.13	-0.14	-0.01
7h	5779.6	6080.25	5287.1	0.07	-0.13	-0.2
23h	5408.92	3663.21	4630.92	-0.56	-0.22	0.34

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	6483.46	5779.6	5408.92	-0.17	-0.26	-0.1
Ebov	5931.41	6080.25	3663.21	0.04	-0.7	-0.73
Marv	5871.25	5287.1	4630.92	-0.15	-0.34	-0.19

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1074.7	1162.98	1041.1	0.11	-0.05	-0.16
7h	967.69	869.41	966.84	-0.15	-0.0	0.15
23h	550.69	542.5	694.64	-0.02	0.34	0.36

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1074.7	967.69	550.69	-0.15	-0.96	-0.81
Ebov	1162.98	869.41	542.5	-0.42	-1.1	-0.68
Marv	1041.1	966.84	694.64	-0.11	-0.58	-0.48

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material