ITGA2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| ITGA2 | GPIa,CD49b | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | NM_002203 |  |
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Description
Homo sapiens integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2). This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 45 | 74 | 59 | 44 | 89 | 50 | 48 | 86 | 68 |
Read_Max |  | R. aegyptiacus | Transcriptome | 169 | 134 | 153 | 125 | 93 | 205 | 100 | 132 | 233 |
Read_Max |  | R. aegyptiacus | Genome | 186 | 129 | 131 | 127 | 80 | 123 | 91 | 151 | 264 |
DESeq | | H. sapiens | Genome | 1320.22 | 1794.96 | 2012.46 | 1359.55 | 1925.25 | 1140.59 | 1275.58 | 1929.03 | 2574.75 |
DESeq | | R. aegyptiacus | Transcriptome | 1820.74 | 1468.73 | 2536.91 | 1811.28 | 1714.82 | 2453.16 | 1598.42 | 1768.26 | 2507.92 |
DESeq | | R. aegyptiacus | Genome | 2050.5 | 2031.64 | 2696.83 | 1823.88 | 1956.58 | 2916.29 | 1922.95 | 1913.38 | 2841.7 |