FGF5

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
FGF5 HBGF-5, Smag-82, TCMGLY fibroblast growth factor 5 pdf NONE NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. No expression in human and in bat homolog.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome7 0 4 0 1 2 1 2 0
Read_Max
batR. aegyptiacusTranscriptome 3 1 3 2 1 NA 4 1 2
Read_Max
bat_genomeR. aegyptiacusGenome 3 2 3 4 2 0 4 3 2
DESeq
humanH. sapiensGenome 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0
DESeq
batR. aegyptiacusTranscriptome 3.52 1.91 5.89 3.75 3.19 1.0 9.9 1.83 2.75
DESeq
bat_genomeR. aegyptiacusGenome 4.3 2.74 3.35 7.9 5.58 0.0 15.74 4.76 3.42

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 1.0 1.0 0.0 0.0 0.0
7h 1.0 1.0 1.0 0.0 0.0 0.0
23h 1.0 1.0 1.0 0.0 0.0 0.0

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 1.0 1.0 0.0 0.0 0.0
Ebov 1.0 1.0 1.0 0.0 0.0 0.0
Marv 1.0 1.0 1.0 0.0 0.0 0.0

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3.52 3.75 9.9 0.09 1.49 1.4
7h 1.91 3.19 1.83 0.74 -0.06 -0.8
23h 5.89 1.0 2.75 -2.56 -1.1 1.46

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3.52 1.91 5.89 -0.88 0.74 1.62
Ebov 3.75 3.19 1.0 -0.23 -1.91 -1.67
Marv 9.9 1.83 2.75 -2.44 -1.85 0.59