FGF22

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
FGF22 fibroblast growth factor 22 pdf NONE NONE NONE

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Description

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. No expression in human and no homolog found.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome7 3 2 6 3 3 6 4 1
Read_Max
batR. aegyptiacusTranscriptome 3 5 4 5 5 4 4 8 6
Read_Max
bat_genomeR. aegyptiacusGenome 6 7 5 5 7 2 4 10 11
DESeq
humanH. sapiensGenome 52.75 17.32 7.95 39.78 14.01 6.26 44.86 25.78 4.26
DESeq
batR. aegyptiacusTranscriptome 5.2 9.17 19.32 10.16 13.05 12.55 11.01 15.87 10.62
DESeq
bat_genomeR. aegyptiacusGenome 21.48 24.64 45.75 21.72 42.41 27.41 32.61 27.75 32.54

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 52.75 39.78 44.86 -0.41 -0.23 0.17
7h 17.32 14.01 25.78 -0.31 0.57 0.88
23h 7.95 6.26 4.26 -0.34 -0.9 -0.56

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 52.75 17.32 7.95 -1.61 -2.73 -1.12
Ebov 39.78 14.01 6.26 -1.51 -2.67 -1.16
Marv 44.86 25.78 4.26 -0.8 -3.4 -2.6

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 5.2 10.16 11.01 0.97 1.08 0.12
7h 9.17 13.05 15.87 0.51 0.79 0.28
23h 19.32 12.55 10.62 -0.62 -0.86 -0.24

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 5.2 9.17 19.32 0.82 1.89 1.08
Ebov 10.16 13.05 12.55 0.36 0.3 -0.06
Marv 11.01 15.87 10.62 0.53 -0.05 -0.58