ITGA5
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| ITGA5 | ITGA5, CD49e, FNRA, VLA5A,CD49e | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Expression of this gene is slightly increased over time in control, EBOV and MARV. There is an intron retention in EBOV 23h. Bat homolog is uniformely expressed.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 30 | 58 | 66 | 49 | 76 | 75 | 45 | 81 | 96 |
Read_Max |  | R. aegyptiacus | Transcriptome | 410 | 424 | 376 | 391 | 310 | 364 | 274 | 459 | 565 |
Read_Max |  | R. aegyptiacus | Genome | 468 | 405 | 327 | 417 | 270 | 219 | 237 | 546 | 654 |
DESeq | | H. sapiens | Genome | 751.94 | 1305.42 | 1238.06 | 948.91 | 1148.07 | 1481.41 | 795.75 | 1374.28 | 2201.79 |
DESeq | | R. aegyptiacus | Transcriptome | 5401.42 | 6373.89 | 6157.55 | 5252.36 | 5081.12 | 5806.11 | 4781.01 | 5409.36 | 5991.88 |
DESeq | | R. aegyptiacus | Genome | 6666.29 | 6209.91 | 7026.05 | 8120.08 | 6097.44 | 7225.44 | 6090.47 | 6208.77 | 7015.63 |