CCNA2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CCNA2 CCN1, CCNA, cyca2 cyclin A2 NM_001237 pdf

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Description

Homo sapiens cyclin A2 (CCNA2), mRNA. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. [provided by RefSeq, Jul 2008].

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome647 506 509 529 692 356 680 582 353
Read_Max
batR. aegyptiacusTranscriptome 839 879 376 665 648 555 913 861 599
Read_Max
bat_genomeR. aegyptiacusGenome 1506 1126 525 1382 909 552 1248 1734 1010
DESeq
humanH. sapiensGenome 7316.6 5978.48 6038.37 6849.66 6792.39 3748.75 6519.51 5676.39 5084.35
DESeq
batR. aegyptiacusTranscriptome 4414.26 4576.66 2180.22 3849.55 4016.69 2750.86 5763.26 3851.96 2371.46
DESeq
bat_genomeR. aegyptiacusGenome 7269.58 6051.1 3248.03 7811.0 6546.13 4567.63 9096.34 6103.31 3786.94

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7316.6 6849.66 6519.51 -0.1 -0.17 -0.07
7h 5978.48 6792.39 5676.39 0.18 -0.07 -0.26
23h 6038.37 3748.75 5084.35 -0.69 -0.25 0.44

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7316.6 5978.48 6038.37 -0.29 -0.28 0.01
Ebov 6849.66 6792.39 3748.75 -0.01 -0.87 -0.86
Marv 6519.51 5676.39 5084.35 -0.2 -0.36 -0.16

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 4414.26 3849.55 5763.26 -0.2 0.38 0.58
7h 4576.66 4016.69 3851.96 -0.19 -0.25 -0.06
23h 2180.22 2750.86 2371.46 0.34 0.12 -0.21

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 4414.26 4576.66 2180.22 0.05 -1.02 -1.07
Ebov 3849.55 4016.69 2750.86 0.06 -0.48 -0.55
Marv 5763.26 3851.96 2371.46 -0.58 -1.28 -0.7