PIK3R4

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
PIK3R4 VPS15, p150 phosphoinositide-3-kinase, regulatory subunit 4 NM_014602 pdf

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Description

The phosphoinositide-3-kinase, regulatory subunit 4 (EC:2.7.11.1) gene is involved in the regulation of autophagy. This gene did not present any interesting differential gene expression pattern in the samples analyzed. Only a slightly downregulation after 23 hours of Ebola infection in humans.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome95 124 123 92 145 86 122 147 107
Read_Max
batR. aegyptiacusTranscriptome 130 111 69 107 88 96 85 138 114
Read_Max
bat_genomeR. aegyptiacusGenome 143 105 50 87 74 61 75 134 111
DESeq
humanH. sapiensGenome 2457.8 2695.5 2908.98 2488.83 2975.59 1632.74 2341.38 2530.14 2667.17
DESeq
batR. aegyptiacusTranscriptome 1932.48 1700.2 1527.92 2115.28 2013.78 1936.04 1911.0 2069.83 1767.91
DESeq
bat_genomeR. aegyptiacusGenome 2429.5 2573.77 1860.0 2321.57 2540.32 2431.98 2377.26 2512.05 2127.64

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2457.8 2488.83 2341.38 0.02 -0.07 -0.09
7h 2695.5 2975.59 2530.14 0.14 -0.09 -0.23
23h 2908.98 1632.74 2667.17 -0.83 -0.13 0.71

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2457.8 2695.5 2908.98 0.13 0.24 0.11
Ebov 2488.83 2975.59 1632.74 0.26 -0.61 -0.87
Marv 2341.38 2530.14 2667.17 0.11 0.19 0.08

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1932.48 2115.28 1911.0 0.13 -0.02 -0.15
7h 1700.2 2013.78 2069.83 0.24 0.28 0.04
23h 1527.92 1936.04 1767.91 0.34 0.21 -0.13

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1932.48 1700.2 1527.92 -0.18 -0.34 -0.15
Ebov 2115.28 2013.78 1936.04 -0.07 -0.13 -0.06
Marv 1911.0 2069.83 1767.91 0.12 -0.11 -0.23