SOCS5

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
SOCS5 CIS6, CISH5, CISH6, KIAA0671, NM_014011, NP_659198, O75159, Q53SD4, Q8IYZ4, SOCS5_HUMAN,KIAA0671, SOCS-5, CIS6, Cish5 suppressor of cytokine signaling 5 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

There were no strong changes concerning the expression and pattern within this gene.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome68 70 84 63 76 130 82 100 74
Read_Max
batR. aegyptiacusTranscriptome 318 251 277 243 227 261 199 317 365
Read_Max
bat_genomeR. aegyptiacusGenome 378 276 246 258 217 157 191 411 346
DESeq
humanH. sapiensGenome 996.51 963.76 1098.07 851.95 970.85 1316.92 1008.03 985.8 1240.58
DESeq
batR. aegyptiacusTranscriptome 1876.19 1616.69 2095.94 1666.6 1664.44 1610.11 1987.76 1863.27 1948.98
DESeq
bat_genomeR. aegyptiacusGenome 3357.64 3021.9 3617.35 3056.26 3304.87 3236.11 3697.46 3543.68 3598.57

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 996.51 851.95 1008.03 -0.23 0.02 0.24
7h 963.76 970.85 985.8 0.01 0.03 0.02
23h 1098.07 1316.92 1240.58 0.26 0.18 -0.09

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 996.51 963.76 1098.07 -0.05 0.14 0.19
Ebov 851.95 970.85 1316.92 0.19 0.63 0.44
Marv 1008.03 985.8 1240.58 -0.03 0.3 0.33

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1876.19 1666.6 1987.76 -0.17 0.08 0.25
7h 1616.69 1664.44 1863.27 0.04 0.2 0.16
23h 2095.94 1610.11 1948.98 -0.38 -0.1 0.28

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1876.19 1616.69 2095.94 -0.21 0.16 0.37
Ebov 1666.6 1664.44 1610.11 -0.0 -0.05 -0.05
Marv 1987.76 1863.27 1948.98 -0.09 -0.03 0.06