HIST1H1C

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
HIST1H1C H1.2, H1s-1, H1c histone cluster 1, H1c NM_005319 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.

The gene seems to be down-regulated in human cell samples after 23h p.i. with EBOV or MARV.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome101 110 121 120 173 101 137 170 77
Read_Max
batR. aegyptiacusTranscriptome 18 26 78 30 38 19 19 28 40
Read_Max
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA
DESeq
humanH. sapiensGenome 334.86 390.59 413.02 472.1 474.14 299.71 493.11 503.79 319.59
DESeq
batR. aegyptiacusTranscriptome 58.13 84.51 300.28 95.31 138.98 69.01 78.87 81.14 92.84
DESeq
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 334.86 472.1 493.11 0.5 0.56 0.06
7h 390.59 474.14 503.79 0.28 0.37 0.09
23h 413.02 299.71 319.59 -0.46 -0.37 0.09

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 334.86 390.59 413.02 0.22 0.3 0.08
Ebov 472.1 474.14 299.71 0.01 -0.66 -0.66
Marv 493.11 503.79 319.59 0.03 -0.63 -0.66

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 58.13 95.31 78.87 0.71 0.44 -0.27
7h 84.51 138.98 81.14 0.72 -0.06 -0.78
23h 300.28 69.01 92.84 -2.12 -1.69 0.43

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 58.13 84.51 300.28 0.54 2.37 1.83
Ebov 95.31 138.98 69.01 0.54 -0.47 -1.01
Marv 78.87 81.14 92.84 0.04 0.24 0.19