LZTS1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| LZTS1 | F37, FEZ1,FEZ1 | leucine zipper, putative tumor suppressor 1 | NM_021020 |  |
 |
NONE |  |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex.
Expression level is rapidly decreased in Ebola infected human cells after 23 h.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 24 | 15 | 10 | 20 | 14 | 3 | 17 | 19 | 7 |
Read_Max |  | R. aegyptiacus | Transcriptome | 68 | 51 | 41 | 52 | 49 | 45 | 39 | 57 | 58 |
Read_Max |  | R. aegyptiacus | Genome | 73 | 57 | 39 | 68 | 50 | 29 | 40 | 87 | 84 |
DESeq | | H. sapiens | Genome | 466.79 | 298.8 | 163.82 | 413.93 | 212.37 | 11.53 | 368.55 | 239.21 | 67.33 |
DESeq | | R. aegyptiacus | Transcriptome | 450.48 | 483.89 | 423.65 | 434.11 | 479.55 | 315.38 | 390.34 | 452.11 | 468.09 |
DESeq | | R. aegyptiacus | Genome | 1549.48 | 1584.42 | 1704.91 | 1682.67 | 1619.51 | 1435.95 | 1458.52 | 1505.8 | 1822.83 |