CIDEC

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CIDEC CIDE-3, FLJ20871, Fsp27 cell death-inducing DFFA-like effector c NM_022094 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.

It is expressed very weak in human cells under all investigated conditions and shows a slight upregulation after 23 h of Marburg virus infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome4 3 3 6 2 5 7 6 47
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 2 2 2 0 3 2 1 4 2
DESeq
humanH. sapiensGenome 15.21 13.24 8.94 16.97 4.25 7.58 16.79 21.78 219.56
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 7.73 10.95 4.46 0.0 11.16 5.22 1.12 7.14 5.99

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 15.21 16.97 16.79 0.16 0.14 -0.02
7h 13.24 4.25 21.78 -1.64 0.72 2.36
23h 8.94 7.58 219.56 -0.24 4.62 4.86

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 15.21 13.24 8.94 -0.2 -0.77 -0.57
Ebov 16.97 4.25 7.58 -2.0 -1.16 0.83
Marv 16.79 21.78 219.56 0.38 3.71 3.33

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA