HMGCS2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| HMGCS2 | B7Z8R3, HMCS2_HUMAN, NM_005518, NP_005509, P54868, Q5SZU2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | NM_005518 |  |
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NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene belongs to the HMG-CoA synthase family. Itis a mitochondrial enzyme that catalyzes the first reaction of ketogenesis,a metabolic pathway that provides lipid-derived energy for various organsduring times of carbohydrate deprivation, such as fasting. Mutations in thisgene are associated with HMG-CoA synthase deficiency.
The gene is equally expressed in all human cells probes. We found no homolog inbat cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 11 | 17 | 10 | 18 | 13 | 3 | 14 | 16 | 3 |
Read_Max |  | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Read_Max |  | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | H. sapiens | Genome | 131.91 | 104.01 | 93.33 | 144.73 | 96.12 | 6.26 | 101.88 | 101.72 | 22.75 |
DESeq | | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |