DAPK3

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
DAPK3	ZIP, ZIPK	death-associated protein kinase 3	NM_001348	pdf		NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

DAPK3 seem to be upregulated in the human ebola 23h sample. Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	60	81	60	88	74	619	120	123	104
Read_Max	R. aegyptiacus	Transcriptome	270	268	304	281	255	358	215	322	333
Read_Max	R. aegyptiacus	Genome	370	314	355	328	248	247	213	458	450
DESeq	H. sapiens	Genome	663.66	798.54	595.7	898.72	586.32	5283.11	946.63	1000.99	1033.98
DESeq	R. aegyptiacus	Transcriptome	2161.0	2224.84	3241.74	2244.39	2427.72	3178.16	2272.53	2523.41	2606.76
DESeq	R. aegyptiacus	Genome	3010.44	3098.57	4244.42	3177.72	3351.75	4365.29	3009.25	3371.61	3393.94

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	663.66	898.72	946.63	0.44	0.51	0.07
7h	798.54	586.32	1000.99	-0.45	0.33	0.77
23h	595.7	5283.11	1033.98	3.15	0.8	-2.35

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	663.66	798.54	595.7	0.27	-0.16	-0.42
Ebov	898.72	586.32	5283.11	-0.62	2.56	3.17
Marv	946.63	1000.99	1033.98	0.08	0.13	0.05

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	2161.0	2244.39	2272.53	0.05	0.07	0.02
7h	2224.84	2427.72	2523.41	0.13	0.18	0.06
23h	3241.74	3178.16	2606.76	-0.03	-0.31	-0.29

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	2161.0	2224.84	3241.74	0.04	0.59	0.54
Ebov	2244.39	2427.72	3178.16	0.11	0.5	0.39
Marv	2272.53	2523.41	2606.76	0.15	0.2	0.05

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material