RHOB

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
RHOB	RhoB, RHOH6, MST081	ras homolog family member B	NM_004040	pdf		NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens ras homolog family member B (RHOB), mRNA. The gene is highly expressed in bat and human.

It is upregulated upon infection of Marburg in bat cells, but slighlty downregulated in Ebola infected bat cells. In human cells it is stably expressed, with the exception of a three times increase expression due to Ebola infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	376	196	171	228	388	1560	375	333	388
Read_Max	R. aegyptiacus	Transcriptome	198	277	398	323	306	305	255	371	528
Read_Max	R. aegyptiacus	Genome	215	305	294	254	251	163	217	417	530
DESeq	H. sapiens	Genome	3824.72	2428.3	1762.27	3231.41	2755.28	13466.83	3514.21	3134.45	3368.51
DESeq	R. aegyptiacus	Transcriptome	922.63	1194.61	2009.21	1334.21	1577.93	1311.13	1384.83	1517.92	2177.28
DESeq	R. aegyptiacus	Genome	1158.46	1620.93	2358.75	1653.05	2062.62	1732.28	1748.65	1787.3	2643.06

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3824.72	3231.41	3514.21	-0.24	-0.12	0.12
7h	2428.3	2755.28	3134.45	0.18	0.37	0.19
23h	1762.27	13466.83	3368.51	2.93	0.93	-2.0

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3824.72	2428.3	1762.27	-0.66	-1.12	-0.46
Ebov	3231.41	2755.28	13466.83	-0.23	2.06	2.29
Marv	3514.21	3134.45	3368.51	-0.16	-0.06	0.1

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	922.63	1334.21	1384.83	0.53	0.59	0.05
7h	1194.61	1577.93	1517.92	0.4	0.35	-0.06
23h	2009.21	1311.13	2177.28	-0.62	0.12	0.73

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	922.63	1194.61	2009.21	0.37	1.12	0.75
Ebov	1334.21	1577.93	1311.13	0.24	-0.03	-0.27
Marv	1384.83	1517.92	2177.28	0.13	0.65	0.52

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material