SEL1L3

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
SEL1L3 B4DTH5,KIAA0746 sel-1 suppressor of lin-12-like 3 (C. elegans) NM_015187 pdf

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Description

The sel-1 suppressor of lin-12-like 3 (SEL1L3) gene is equally expressed in human cells within the wildtype, whereas for the infected samples differential expression was observed. Within the Ebola cells the expression first increased twice (7 h) and than decreased again (3x, 23 h). For the Marburg infected cells a slight upregulation was observed.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome128 153 155 107 233 78 180 262 498
Read_Max
batR. aegyptiacusTranscriptome 31 9 21 19 15 22 12 15 31
Read_Max
bat_genomeR. aegyptiacusGenome 21 13 15 9 13 12 8 18 29
DESeq
humanH. sapiensGenome 2547.1 3054.5 2596.24 2618.87 3053.63 1278.76 2941.39 4162.42 9044.46
DESeq
batR. aegyptiacusTranscriptome 140.46 70.89 275.85 138.35 141.17 189.63 116.69 150.54 256.41
DESeq
bat_genomeR. aegyptiacusGenome 130.63 120.47 228.73 81.96 136.17 172.31 106.83 145.11 235.45

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2547.1 2618.87 2941.39 0.04 0.21 0.17
7h 3054.5 3053.63 4162.42 -0.0 0.45 0.45
23h 2596.24 1278.76 9044.46 -1.02 1.8 2.82

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2547.1 3054.5 2596.24 0.26 0.03 -0.23
Ebov 2618.87 3053.63 1278.76 0.22 -1.03 -1.26
Marv 2941.39 4162.42 9044.46 0.5 1.62 1.12

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 140.46 138.35 116.69 -0.02 -0.27 -0.25
7h 70.89 141.17 150.54 0.99 1.09 0.09
23h 275.85 189.63 256.41 -0.54 -0.11 0.44

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 140.46 70.89 275.85 -0.99 0.97 1.96
Ebov 138.35 141.17 189.63 0.03 0.45 0.43
Marv 116.69 150.54 256.41 0.37 1.14 0.77