SEL1L3

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
SEL1L3	B4DTH5,KIAA0746	sel-1 suppressor of lin-12-like 3 (C. elegans)	NM_015187	pdf

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Description

The sel-1 suppressor of lin-12-like 3 (SEL1L3) gene is equally expressed in human cells within the wildtype, whereas for the infected samples differential expression was observed. Within the Ebola cells the expression first increased twice (7 h) and than decreased again (3x, 23 h). For the Marburg infected cells a slight upregulation was observed.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	128	153	155	107	233	78	180	262	498
Read_Max	R. aegyptiacus	Transcriptome	31	9	21	19	15	22	12	15	31
Read_Max	R. aegyptiacus	Genome	21	13	15	9	13	12	8	18	29
DESeq	H. sapiens	Genome	2547.1	3054.5	2596.24	2618.87	3053.63	1278.76	2941.39	4162.42	9044.46
DESeq	R. aegyptiacus	Transcriptome	140.46	70.89	275.85	138.35	141.17	189.63	116.69	150.54	256.41
DESeq	R. aegyptiacus	Genome	130.63	120.47	228.73	81.96	136.17	172.31	106.83	145.11	235.45

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	2547.1	2618.87	2941.39	0.04	0.21	0.17
7h	3054.5	3053.63	4162.42	-0.0	0.45	0.45
23h	2596.24	1278.76	9044.46	-1.02	1.8	2.82

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	2547.1	3054.5	2596.24	0.26	0.03	-0.23
Ebov	2618.87	3053.63	1278.76	0.22	-1.03	-1.26
Marv	2941.39	4162.42	9044.46	0.5	1.62	1.12

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	140.46	138.35	116.69	-0.02	-0.27	-0.25
7h	70.89	141.17	150.54	0.99	1.09	0.09
23h	275.85	189.63	256.41	-0.54	-0.11	0.44

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	140.46	70.89	275.85	-0.99	0.97	1.96
Ebov	138.35	141.17	189.63	0.03	0.45	0.43
Marv	116.69	150.54	256.41	0.37	1.14	0.77

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material