SLC9A1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
SLC9A1 AK124218, NM_003047, NP_003038, Q5TBB3, Q5TBB3_HUMAN, RP4-633N17.1-003,PPP1R143 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 NM_003047 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 (SLC9A1), transcript variant 2 gene encodes a Na+/H+ antiporter that is a member of the solute carrier family 9. The encoded protein is a plasma membrane transporter that is expressed in the kidney and intestine. This protein plays a central role in regulating pH homeostasis, cell migration and cell volume. This protein may also be involved in tumor growth.

In HG19 MOCK this gene is downregulated, but upregulated during ebola infection, while marburg infection doesn't affect the expression level. In the RAE samples the amount of transcripts increase for ebola and marburg infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome30 27 14 24 32 76 29 29 29
Read_Max
batR. aegyptiacusTranscriptome 60 56 34 41 31 62 39 49 57
Read_Max
bat_genomeR. aegyptiacusGenome 66 45 29 51 28 35 28 59 56
DESeq
humanH. sapiensGenome 636.26 479.32 348.49 564.5 407.48 1626.16 507.15 487.8 419.63
DESeq
batR. aegyptiacusTranscriptome 702.52 670.88 591.0 499.12 491.6 819.67 551.64 435.59 568.69
DESeq
bat_genomeR. aegyptiacusGenome 1193.69 894.43 1009.78 1223.49 856.07 1433.34 965.97 812.77 1066.81

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 636.26 564.5 507.15 -0.17 -0.33 -0.15
7h 479.32 407.48 487.8 -0.23 0.03 0.26
23h 348.49 1626.16 419.63 2.22 0.27 -1.95

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 636.26 479.32 348.49 -0.41 -0.87 -0.46
Ebov 564.5 407.48 1626.16 -0.47 1.53 2.0
Marv 507.15 487.8 419.63 -0.06 -0.27 -0.22

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 702.52 499.12 551.64 -0.49 -0.35 0.14
7h 670.88 491.6 435.59 -0.45 -0.62 -0.17
23h 591.0 819.67 568.69 0.47 -0.06 -0.53

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 702.52 670.88 591.0 -0.07 -0.25 -0.18
Ebov 499.12 491.6 819.67 -0.02 0.72 0.74
Marv 551.64 435.59 568.69 -0.34 0.04 0.38