RELN

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RELN LIS2, PRO1598, RL,RL reelin NM_005045 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia.

This gene is upregulated in Ebola infected cells in human cells. No homolog in bat cells was found.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome152 195 254 151 396 816 158 198 238
Read_Max
batR. aegyptiacusTranscriptome 1 NA NA 2 NA 1 2 1 NA
Read_Max
bat_genomeR. aegyptiacusGenome 2 2 2 3 2 2 2 3 2
DESeq
humanH. sapiensGenome 7858.49 9827.48 10010.66 7237.49 10071.83 32406.9 6906.36 7945.74 8900.93
DESeq
batR. aegyptiacusTranscriptome 1.84 1.0 1.0 2.83 1.0 2.28 3.22 2.65 1.0
DESeq
bat_genomeR. aegyptiacusGenome 11.17 24.64 16.74 7.9 15.63 18.28 13.49 11.1 10.27

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7858.49 7237.49 6906.36 -0.12 -0.19 -0.07
7h 9827.48 10071.83 7945.74 0.04 -0.31 -0.34
23h 10010.66 32406.9 8900.93 1.69 -0.17 -1.86

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7858.49 9827.48 10010.66 0.32 0.35 0.03
Ebov 7237.49 10071.83 32406.9 0.48 2.16 1.69
Marv 6906.36 7945.74 8900.93 0.2 0.37 0.16

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.84 2.83 3.22 0.62 0.81 0.19
7h 1.0 1.0 2.65 0.0 1.41 1.41
23h 1.0 2.28 1.0 1.19 0.0 -1.19

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.84 1.0 1.0 -0.88 -0.88 0.0
Ebov 2.83 1.0 2.28 -1.5 -0.31 1.19
Marv 3.22 2.65 1.0 -0.28 -1.69 -1.41