MICAL3

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
MICAL3	KIAA0819	microtubule associated monooxygenase, calponin and LIM domain containing 3		pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens microtubule associated monooxygenase, calponin and LIM domain containing 3 (MICAL3).

We observed an upregulation of MICAL3 in the human cells cells after 23 h of Ebola infection, whereas the homologous transcript in bat cells seems to be equally expressed.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	88	133	113	91	144	509	120	159	114
Read_Max	R. aegyptiacus	Transcriptome	28	22	17	23	26	26	22	26	18
Read_Max	R. aegyptiacus	Genome	121	117	63	86	71	51	81	135	105
DESeq	H. sapiens	Genome	3963.74	5071.81	4129.16	4427.99	4876.27	18148.88	4464.22	5317.48	5272.46
DESeq	R. aegyptiacus	Transcriptome	302.61	286.92	187.9	283.94	283.53	285.87	255.74	256.3	204.81
DESeq	R. aegyptiacus	Genome	3911.08	3333.13	2809.53	3639.86	3353.98	3843.13	3427.57	2998.13	2702.14

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3963.74	4427.99	4464.22	0.16	0.17	0.01
7h	5071.81	4876.27	5317.48	-0.06	0.07	0.12
23h	4129.16	18148.88	5272.46	2.14	0.35	-1.78

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3963.74	5071.81	4129.16	0.36	0.06	-0.3
Ebov	4427.99	4876.27	18148.88	0.14	2.04	1.9
Marv	4464.22	5317.48	5272.46	0.25	0.24	-0.01

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	302.61	283.94	255.74	-0.09	-0.24	-0.15
7h	286.92	283.53	256.3	-0.02	-0.16	-0.15
23h	187.9	285.87	204.81	0.61	0.12	-0.48

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	302.61	286.92	187.9	-0.08	-0.69	-0.61
Ebov	283.94	283.53	285.87	-0.0	0.01	0.01
Marv	255.74	256.3	204.81	0.0	-0.32	-0.32

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material