TRIM8

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TRIM8 A6NI31, GERP, NM_030912, NP_112174, Q9BZR9, Q9C028, RNF27, TRIM8_HUMAN,GERP tripartite motif containing 8 NM_030912 pdf

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Description

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.

While this gene does not show any differential expression for MOCK and MARV samples, there is a strong upregulation for EBOV-infected cells between 7 h and 23 h p.i.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome108 110 113 121 118 414 127 139 120
Read_Max
batR. aegyptiacusTranscriptome 437 327 305 346 296 648 401 455 523
Read_Max
bat_genomeR. aegyptiacusGenome 461 337 263 313 250 390 341 544 635
DESeq
humanH. sapiensGenome 1385.17 1182.01 1352.23 1482.75 1109.05 4817.28 1265.05 1287.95 1472.18
DESeq
batR. aegyptiacusTranscriptome 3870.69 3222.39 3522.69 3204.01 3232.61 6038.37 4065.73 3476.03 3917.07
DESeq
bat_genomeR. aegyptiacusGenome 6095.65 5142.07 5563.27 5405.49 5350.75 9725.3 6675.22 5407.89 6261.33

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1385.17 1482.75 1265.05 0.1 -0.13 -0.23
7h 1182.01 1109.05 1287.95 -0.09 0.12 0.22
23h 1352.23 4817.28 1472.18 1.83 0.12 -1.71

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1385.17 1182.01 1352.23 -0.23 -0.03 0.19
Ebov 1482.75 1109.05 4817.28 -0.42 1.7 2.12
Marv 1265.05 1287.95 1472.18 0.03 0.22 0.19

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3870.69 3204.01 4065.73 -0.27 0.07 0.34
7h 3222.39 3232.61 3476.03 0.0 0.11 0.1
23h 3522.69 6038.37 3917.07 0.78 0.15 -0.62

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3870.69 3222.39 3522.69 -0.26 -0.14 0.13
Ebov 3204.01 3232.61 6038.37 0.01 0.91 0.9
Marv 4065.73 3476.03 3917.07 -0.23 -0.05 0.17