PRKAA2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
PRKAA2 AMPK subunit alpha2,AMPK, AMPKa2 protein kinase, AMP-activated, alpha 2 catalytic subunit NM_006252 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.Interesting differential expression of not infected vs infected cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome93 107 106 68 131 314 94 106 124
Read_Max
batR. aegyptiacusTranscriptome 43 42 33 56 48 52 41 53 75
Read_Max
bat_genomeR. aegyptiacusGenome 49 59 20 25 31 18 36 49 43
DESeq
humanH. sapiensGenome 2418.22 2293.67 2420.51 2075.9 2391.89 6549.03 1964.18 1916.24 3191.28
DESeq
batR. aegyptiacusTranscriptome 326.13 256.97 275.85 378.26 330.62 314.1 339.17 304.22 348.26
DESeq
bat_genomeR. aegyptiacusGenome 510.48 579.55 459.7 323.89 491.1 417.73 486.92 470.22 525.7

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2418.22 2075.9 1964.18 -0.22 -0.3 -0.08
7h 2293.67 2391.89 1916.24 0.06 -0.26 -0.32
23h 2420.51 6549.03 3191.28 1.44 0.4 -1.04

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2418.22 2293.67 2420.51 -0.08 0.0 0.08
Ebov 2075.9 2391.89 6549.03 0.2 1.66 1.45
Marv 1964.18 1916.24 3191.28 -0.04 0.7 0.74

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 326.13 378.26 339.17 0.21 0.06 -0.16
7h 256.97 330.62 304.22 0.36 0.24 -0.12
23h 275.85 314.1 348.26 0.19 0.34 0.15

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 326.13 256.97 275.85 -0.34 -0.24 0.1
Ebov 378.26 330.62 314.1 -0.19 -0.27 -0.07
Marv 339.17 304.22 348.26 -0.16 0.04 0.2