G3BP1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
G3BP1 hDHVIII,HDH-VIII, G3BP GTPase activating protein (SH3 domain) binding protein 1 NM_005754 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion The gene expression profile of this gene in bats seems to be independent of infection, contrary to humans.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome850 848 669 774 1045 341 862 1115 629
Read_Max
batR. aegyptiacusTranscriptome 1473 1126 724 958 889 898 1109 1249 939
Read_Max
bat_genomeR. aegyptiacusGenome 1669 1041 741 1131 775 527 976 1557 1133
DESeq
humanH. sapiensGenome 10991.14 9769.34 9474.53 9701.37 10487.25 3438.19 9189.72 9007.28 9513.11
DESeq
batR. aegyptiacusTranscriptome 9130.81 7823.47 5659.16 7171.6 7181.5 5895.94 8991.47 7182.4 5490.67
DESeq
bat_genomeR. aegyptiacusGenome 26193.35 22857.28 15379.88 23654.18 24354.04 21581.04 29346.91 22620.37 17348.16

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 10991.14 9701.37 9189.72 -0.18 -0.26 -0.08
7h 9769.34 10487.25 9007.28 0.1 -0.12 -0.22
23h 9474.53 3438.19 9513.11 -1.46 0.01 1.47

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 10991.14 9769.34 9474.53 -0.17 -0.21 -0.04
Ebov 9701.37 10487.25 3438.19 0.11 -1.5 -1.61
Marv 9189.72 9007.28 9513.11 -0.03 0.05 0.08

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 9130.81 7171.6 8991.47 -0.35 -0.02 0.33
7h 7823.47 7181.5 7182.4 -0.12 -0.12 0.0
23h 5659.16 5895.94 5490.67 0.06 -0.04 -0.1

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 9130.81 7823.47 5659.16 -0.22 -0.69 -0.47
Ebov 7171.6 7181.5 5895.94 0.0 -0.28 -0.28
Marv 8991.47 7182.4 5490.67 -0.32 -0.71 -0.39