TP53BP2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TP53BP2 Bbp,53BP2, p53BP2,PPP1R13A, ASPP2, 53BP2 tumor protein p53 binding protein 2 NM_001031685, NM_005426 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Seems there is differential alternative splicing. Interesting differential expression in ebola infected human cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome192 201 193 197 271 562 265 304 240
Read_Max
batR. aegyptiacusTranscriptome 193 189 138 195 135 161 134 236 149
Read_Max
bat_genomeR. aegyptiacusGenome 1441 1055 469 1137 804 625 1115 1491 1127
DESeq
humanH. sapiensGenome 4083.49 3570.56 3220.73 4161.07 3650.34 9471.69 4260.71 3705.19 4546.11
DESeq
batR. aegyptiacusTranscriptome 2754.14 3027.24 2655.4 2812.1 2714.63 2766.26 2727.51 2773.76 2433.57
DESeq
bat_genomeR. aegyptiacusGenome 9967.21 8069.96 6248.36 10319.2 9151.18 9761.86 11363.4 8412.36 8040.5

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 4083.49 4161.07 4260.71 0.03 0.06 0.03
7h 3570.56 3650.34 3705.19 0.03 0.05 0.02
23h 3220.73 9471.69 4546.11 1.56 0.5 -1.06

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 4083.49 3570.56 3220.73 -0.19 -0.34 -0.15
Ebov 4161.07 3650.34 9471.69 -0.19 1.19 1.38
Marv 4260.71 3705.19 4546.11 -0.2 0.09 0.3

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2754.14 2812.1 2727.51 0.03 -0.01 -0.04
7h 3027.24 2714.63 2773.76 -0.16 -0.13 0.03
23h 2655.4 2766.26 2433.57 0.06 -0.13 -0.18

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2754.14 3027.24 2655.4 0.14 -0.05 -0.19
Ebov 2812.1 2714.63 2766.26 -0.05 -0.02 0.03
Marv 2727.51 2773.76 2433.57 0.02 -0.16 -0.19