TP53BP2

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
TP53BP2	Bbp,53BP2, p53BP2,PPP1R13A, ASPP2, 53BP2	tumor protein p53 binding protein 2	NM_001031685, NM_005426	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Seems there is differential alternative splicing. Interesting differential expression in ebola infected human cells.

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source		Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max		H. sapiens	Genome	192	201	193	197	271	562	265	304	240
Read_Max		R. aegyptiacus	Transcriptome	193	189	138	195	135	161	134	236	149
Read_Max		R. aegyptiacus	Genome	1441	1055	469	1137	804	625	1115	1491	1127
DESeq		H. sapiens	Genome	4083.49	3570.56	3220.73	4161.07	3650.34	9471.69	4260.71	3705.19	4546.11
DESeq		R. aegyptiacus	Transcriptome	2754.14	3027.24	2655.4	2812.1	2714.63	2766.26	2727.51	2773.76	2433.57
DESeq		R. aegyptiacus	Genome	9967.21	8069.96	6248.36	10319.2	9151.18	9761.86	11363.4	8412.36	8040.5

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	4083.49	4161.07	4260.71	0.03	0.06	0.03
7h	3570.56	3650.34	3705.19	0.03	0.05	0.02
23h	3220.73	9471.69	4546.11	1.56	0.5	-1.06

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	4083.49	3570.56	3220.73	-0.19	-0.34	-0.15
Ebov	4161.07	3650.34	9471.69	-0.19	1.19	1.38
Marv	4260.71	3705.19	4546.11	-0.2	0.09	0.3

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	2754.14	2812.1	2727.51	0.03	-0.01	-0.04
7h	3027.24	2714.63	2773.76	-0.16	-0.13	0.03
23h	2655.4	2766.26	2433.57	0.06	-0.13	-0.18

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	2754.14	3027.24	2655.4	0.14	-0.05	-0.19
Ebov	2812.1	2714.63	2766.26	-0.05	-0.02	0.03
Marv	2727.51	2773.76	2433.57	0.02	-0.16	-0.19