SPRY1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
SPRY1 SPRY1, hSPRY1,hSPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

FROM UNIPROT: May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.

This gene is expressed in human and bat in all different probes. In human it is upregulated after 7h and downregulated after 23h in Ebola and Marburg infected probes. However, in bat after 7h it is downregulated in the Ebola infected probe, but upregulated in the Marburg infected probe.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome87 85 94 58 102 62 81 105 45
Read_Max
batR. aegyptiacusTranscriptome 127 130 157 92 85 74 90 128 134
Read_Max
bat_genomeR. aegyptiacusGenome 137 114 132 126 69 57 101 166 153
DESeq
humanH. sapiensGenome 984.33 1047.39 1634.2 856.51 1335.05 558.95 932.59 1287.15 756.71
DESeq
batR. aegyptiacusTranscriptome 713.44 738.95 1149.24 575.12 544.16 437.28 666.22 623.96 639.54
DESeq
bat_genomeR. aegyptiacusGenome 1987.77 1907.51 3239.1 2069.77 1659.69 1539.08 2111.87 1980.78 1946.98

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 984.33 856.51 932.59 -0.2 -0.08 0.12
7h 1047.39 1335.05 1287.15 0.35 0.3 -0.05
23h 1634.2 558.95 756.71 -1.55 -1.11 0.44

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 984.33 1047.39 1634.2 0.09 0.73 0.64
Ebov 856.51 1335.05 558.95 0.64 -0.62 -1.26
Marv 932.59 1287.15 756.71 0.46 -0.3 -0.77

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 713.44 575.12 666.22 -0.31 -0.1 0.21
7h 738.95 544.16 623.96 -0.44 -0.24 0.2
23h 1149.24 437.28 639.54 -1.39 -0.85 0.55

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 713.44 738.95 1149.24 0.05 0.69 0.64
Ebov 575.12 544.16 437.28 -0.08 -0.4 -0.32
Marv 666.22 623.96 639.54 -0.09 -0.06 0.04