UBR5

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
UBR5	DD5, EDD, EDD1, HYD, KIAA0896	ubiquitin protein ligase E3 component n-recognin 5	NM_015902	pdf

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Description

The ubiquitin protein ligase E3 component n-recognin 5 gene is involved in Ubiquitin mediated proteolysis. It did not show any particular interesting differential expression on the samples analyzed, except for a slight downregulation in the bat control.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	193	191	238	200	240	552	211	235	169
Read_Max	R. aegyptiacus	Transcriptome	265	220	132	236	204	334	228	237	190
Read_Max	R. aegyptiacus	Genome	298	254	128	216	189	220	192	288	211
DESeq	H. sapiens	Genome	8437.94	7697.98	9323.62	7926.47	8414.23	21757.14	7650.23	6603.63	8098.47
DESeq	R. aegyptiacus	Transcriptome	3556.47	3062.64	2408.65	3215.0	3437.39	4375.37	3643.02	2922.47	2439.69
DESeq	R. aegyptiacus	Genome	10212.99	9374.19	6994.81	8771.82	9897.88	12876.56	10649.32	8525.76	6847.82

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	8437.94	7926.47	7650.23	-0.09	-0.14	-0.05
7h	7697.98	8414.23	6603.63	0.13	-0.22	-0.35
23h	9323.62	21757.14	8098.47	1.22	-0.2	-1.43

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	8437.94	7697.98	9323.62	-0.13	0.14	0.28
Ebov	7926.47	8414.23	21757.14	0.09	1.46	1.37
Marv	7650.23	6603.63	8098.47	-0.21	0.08	0.29

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3556.47	3215.0	3643.02	-0.15	0.03	0.18
7h	3062.64	3437.39	2922.47	0.17	-0.07	-0.23
23h	2408.65	4375.37	2439.69	0.86	0.02	-0.84

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3556.47	3062.64	2408.65	-0.22	-0.56	-0.35
Ebov	3215.0	3437.39	4375.37	0.1	0.44	0.35
Marv	3643.02	2922.47	2439.69	-0.32	-0.58	-0.26

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material