EIF2A

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
EIF2A EIF-2A eukaryotic translation initiation factor 2A, 65kDa NM_032025 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes

No abnormalities have been observed. The gene is slightly downregulated in Ebola and Marburg samples from human cells cells. The ENSEMBL annotation misses about 20\,000\,bp at the 3$'$ end.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome186 190 193 190 243 502 221 262 196
Read_Max
batR. aegyptiacusTranscriptome 404 364 172 248 201 232 277 238 252
Read_Max
bat_genomeR. aegyptiacusGenome 439 257 146 336 162 136 235 288 269
DESeq
humanH. sapiensGenome 2317.76 2272.26 2351.02 2406.7 2456.92 5012.03 2409.8 2305.53 2675.87
DESeq
batR. aegyptiacusTranscriptome 2602.91 2573.39 1684.28 2237.06 2310.54 2183.69 2904.38 2164.84 1907.87
DESeq
bat_genomeR. aegyptiacusGenome 3179.74 2878.61 2016.21 3213.27 3029.19 2810.55 3709.83 2785.62 2512.07

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2317.76 2406.7 2409.8 0.05 0.06 0.0
7h 2272.26 2456.92 2305.53 0.11 0.02 -0.09
23h 2351.02 5012.03 2675.87 1.09 0.19 -0.91

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2317.76 2272.26 2351.02 -0.03 0.02 0.05
Ebov 2406.7 2456.92 5012.03 0.03 1.06 1.03
Marv 2409.8 2305.53 2675.87 -0.06 0.15 0.21

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2602.91 2237.06 2904.38 -0.22 0.16 0.38
7h 2573.39 2310.54 2164.84 -0.16 -0.25 -0.09
23h 1684.28 2183.69 1907.87 0.37 0.18 -0.19

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2602.91 2573.39 1684.28 -0.02 -0.63 -0.61
Ebov 2237.06 2310.54 2183.69 0.05 -0.03 -0.08
Marv 2904.38 2164.84 1907.87 -0.42 -0.61 -0.18