ATF6

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
ATF6	ATF6A	activating transcription factor 6	NM_007348	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress.

This gene shows no pronounced response to either Ebola nor Marburg virus infection.

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source		Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max		H. sapiens	Genome	145	146	122	157	192	185	169	171	104
Read_Max		R. aegyptiacus	Transcriptome	113	118	67	122	90	82	64	112	104
Read_Max		R. aegyptiacus	Genome	184	144	66	131	99	56	73	183	153
DESeq		H. sapiens	Genome	2000.13	1792.92	1471.37	2172.86	1723.64	2209.12	1966.82	1625.28	1241.66
DESeq		R. aegyptiacus	Transcriptome	1001.61	1082.06	843.86	1015.56	1041.34	749.09	778.57	971.79	922.07
DESeq		R. aegyptiacus	Genome	1324.32	1243.08	1077.84	1420.99	1327.08	993.42	1012.08	1164.84	1092.5

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	2000.13	2172.86	1966.82	0.12	-0.02	-0.14
7h	1792.92	1723.64	1625.28	-0.06	-0.14	-0.08
23h	1471.37	2209.12	1241.66	0.59	-0.24	-0.83

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	2000.13	1792.92	1471.37	-0.16	-0.44	-0.29
Ebov	2172.86	1723.64	2209.12	-0.33	0.02	0.36
Marv	1966.82	1625.28	1241.66	-0.28	-0.66	-0.39

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1001.61	1015.56	778.57	0.02	-0.36	-0.38
7h	1082.06	1041.34	971.79	-0.06	-0.16	-0.1
23h	843.86	749.09	922.07	-0.17	0.13	0.3

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1001.61	1082.06	843.86	0.11	-0.25	-0.36
Ebov	1015.56	1041.34	749.09	0.04	-0.44	-0.48
Marv	778.57	971.79	922.07	0.32	0.24	-0.08