IL1A
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| IL1A | Interleukin 1, Alpha IL-1 Alpha IL11 IL-1A2hematopoietin-11 IL1-ALPHA2Preinterleukin 1 Alpha1 Interleukin-1 Alpha pro-interleukin-1-alpha ,IL1F1, IL-1A, IL1-ALPHA | interleukin 1, alpha | NM_000575 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
The gene IL1A is very low expressed in all analyzed datasets, and shows awkward read profiles.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 2 | 2 | 4 | 0 | 0 | 3 | 2 | 1 | 2 |
Read_Max |  | R. aegyptiacus | Transcriptome | NA | NA | 2 | NA | NA | NA | NA | 3 | NA |
Read_Max |  | R. aegyptiacus | Genome | 21 | 31 | 13 | 19 | 18 | 9 | 22 | 28 | 21 |
DESeq | | H. sapiens | Genome | 9.12 | 7.12 | 1.99 | 1.0 | 1.0 | 3.63 | 4.51 | 2.6 | 10.79 |
DESeq | | R. aegyptiacus | Transcriptome | 1.0 | 1.0 | 3.44 | 1.0 | 1.0 | 1.0 | 1.0 | 5.13 | 1.0 |
DESeq | | R. aegyptiacus | Genome | 28.36 | 35.59 | 37.94 | 15.8 | 47.99 | 6.53 | 30.36 | 55.51 | 29.11 |