HMOX1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| HMOX1 | CTA-28681B10.6D,HO-1,HSP32,bK286B10, HO-1 | heme oxygenase 1 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
For this gene a slight increase in expression for Marburg infected bat cellss after 23 h was found
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 53 | 84 | 23 | 70 | 76 | 39 | 147 | 243 | 56 |
Read_Max |  | R. aegyptiacus | Transcriptome | 164 | 138 | 184 | 133 | 141 | 199 | 90 | 143 | 342 |
Read_Max |  | R. aegyptiacus | Genome | 197 | 135 | 160 | 140 | 123 | 123 | 75 | 178 | 385 |
DESeq | | H. sapiens | Genome | 430.25 | 552.75 | 197.58 | 545.11 | 439.99 | 261.55 | 886.98 | 1519.77 | 437.03 |
DESeq | | R. aegyptiacus | Transcriptome | 536.17 | 618.23 | 1082.06 | 557.73 | 679.96 | 958.25 | 558.32 | 586.78 | 1462.64 |
DESeq | | R. aegyptiacus | Genome | 831.89 | 765.74 | 1489.56 | 973.66 | 985.55 | 1385.04 | 787.17 | 883.34 | 2159.32 |