RAB14

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RAB14 FBP, RAB-14 RAB14, member RAS oncogene family NM_016322 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes.

RAB14 is highly expressed in both human cells and in the bat cells homolog. There is a slight down-regulation in human cells infected cells after 23 h of Ebola and Marburg infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome425 433 317 383 490 424 463 486 271
Read_Max
batR. aegyptiacusTranscriptome 1014 728 678 757 592 661 751 800 728
Read_Max
bat_genomeR. aegyptiacusGenome 1150 802 598 726 492 402 665 1039 821
DESeq
humanH. sapiensGenome 4231.65 4079.47 4265.18 4070.96 4287.69 3679.0 4037.02 3538.13 3896.96
DESeq
batR. aegyptiacusTranscriptome 3338.04 2665.98 3218.53 3204.01 2996.07 2892.01 3757.6 3153.81 2694.23
DESeq
bat_genomeR. aegyptiacusGenome 9135.32 9288.39 8097.2 7204.68 8682.41 8264.55 11297.05 9542.31 7496.81

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 4231.65 4070.96 4037.02 -0.06 -0.07 -0.01
7h 4079.47 4287.69 3538.13 0.07 -0.21 -0.28
23h 4265.18 3679.0 3896.96 -0.21 -0.13 0.08

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 4231.65 4079.47 4265.18 -0.05 0.01 0.06
Ebov 4070.96 4287.69 3679.0 0.07 -0.15 -0.22
Marv 4037.02 3538.13 3896.96 -0.19 -0.05 0.14

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3338.04 3204.01 3757.6 -0.06 0.17 0.23
7h 2665.98 2996.07 3153.81 0.17 0.24 0.07
23h 3218.53 2892.01 2694.23 -0.15 -0.26 -0.1

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3338.04 2665.98 3218.53 -0.32 -0.05 0.27
Ebov 3204.01 2996.07 2892.01 -0.1 -0.15 -0.05
Marv 3757.6 3153.81 2694.23 -0.25 -0.48 -0.23