ROCK2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ROCK2 ROCK-II Rho-associated, coiled-coil containing protein kinase 2 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.

Well expressed in both human cells and bat cells homolog. No significant differences identified.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome345 315 401 297 495 385 310 338 445
Read_Max
batR. aegyptiacusTranscriptome 388 295 194 344 305 523 354 402 349
Read_Max
bat_genomeR. aegyptiacusGenome 426 337 160 265 241 283 279 454 361
DESeq
humanH. sapiensGenome 7774.27 7539.9 8507.52 7245.48 8040.27 7447.8 6683.55 6805.87 9957.84
DESeq
batR. aegyptiacusTranscriptome 7236.29 5509.77 4405.86 6316.36 6640.53 9773.71 7485.27 5838.16 5425.07
DESeq
bat_genomeR. aegyptiacusGenome 8605.07 7391.84 4839.13 6923.25 7764.94 11624.68 9158.19 6687.71 6301.57

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7774.27 7245.48 6683.55 -0.1 -0.22 -0.12
7h 7539.9 8040.27 6805.87 0.09 -0.15 -0.24
23h 8507.52 7447.8 9957.84 -0.19 0.23 0.42

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7774.27 7539.9 8507.52 -0.04 0.13 0.17
Ebov 7245.48 8040.27 7447.8 0.15 0.04 -0.11
Marv 6683.55 6805.87 9957.84 0.03 0.58 0.55

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7236.29 6316.36 7485.27 -0.2 0.05 0.24
7h 5509.77 6640.53 5838.16 0.27 0.08 -0.19
23h 4405.86 9773.71 5425.07 1.15 0.3 -0.85

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7236.29 5509.77 4405.86 -0.39 -0.72 -0.32
Ebov 6316.36 6640.53 9773.71 0.07 0.63 0.56
Marv 7485.27 5838.16 5425.07 -0.36 -0.46 -0.11