ZNF445

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
ZNF445	ZKSCAN15, ZNF168, ZSCAN47	zinc finger protein 445	NM_181489	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

May be involved in transcriptional regulation (uniprot).

The gene is downregulated to half the level 23 h after infection with Ebola virus in human cells and only slightly downregulated in bat cells 23 h after infection. %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%

\igvfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00411/snapshots//hg19.goi.00411_igv.eps % \caption\igv of gene ZNF445. % <- say something about the figure here \endfigure }

\sashimifigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00411/snapshots//hg19.goi.00411_sashimi.eps % \caption\sashimi of gene ZNF445. % <- say something about the figure here \endfigure }

\ucscfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.goi.00411/snapshots//hg19.goi.00411_ucsc.eps % \caption\ucsc of gene ZNF445. % <- say something about the figure here \endfigure }

\setcounterfigure0 \enddocument

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	236	184	209	184	225	112	207	200	132
Read_Max	R. aegyptiacus	Transcriptome	155	112	65	101	71	89	100	96	72
Read_Max	R. aegyptiacus	Genome	156	101	60	106	61	73	85	119	106
DESeq	H. sapiens	Genome	10211.79	7540.92	7441.23	8188.82	7206.18	3626.37	7934.44	6333.45	5798.73
DESeq	R. aegyptiacus	Transcriptome	1390.59	1348.01	1243.3	1311.32	1255.97	1490.77	1219.08	1233.7	1103.13
DESeq	R. aegyptiacus	Genome	2300.59	2042.59	1907.98	2268.25	2107.26	2532.5	2303.04	1966.51	1869.07

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	10211.79	8188.82	7934.44	-0.32	-0.36	-0.05
7h	7540.92	7206.18	6333.45	-0.07	-0.25	-0.19
23h	7441.23	3626.37	5798.73	-1.04	-0.36	0.68

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	10211.79	7540.92	7441.23	-0.44	-0.46	-0.02
Ebov	8188.82	7206.18	3626.37	-0.18	-1.18	-0.99
Marv	7934.44	6333.45	5798.73	-0.33	-0.45	-0.13

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1390.59	1311.32	1219.08	-0.08	-0.19	-0.11
7h	1348.01	1255.97	1233.7	-0.1	-0.13	-0.03
23h	1243.3	1490.77	1103.13	0.26	-0.17	-0.43

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1390.59	1348.01	1243.3	-0.04	-0.16	-0.12
Ebov	1311.32	1255.97	1490.77	-0.06	0.19	0.25
Marv	1219.08	1233.7	1103.13	0.02	-0.14	-0.16

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material