TGFB3
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| TGFB3 | ARVD1, RNHF, TGF-beta3 | transforming growth factor, beta 3 | NM_003239 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and is involved in embryogenesis and cell differentiation. Defects in this gene are a cause of familial arrhythmogenic right ventricular dysplasia 1.
The gene is very lowly but stably expressed in human cells. The bat cells homolog is morw highly expressed and shows downregulation in Ebola after 23 h and upregulation in Marburg after 23 h.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 20 | 6 | 12 | 10 | 10 | 15 | 10 | 13 | 8 |
Read_Max |  | R. aegyptiacus | Transcriptome | 92 | 63 | 108 | 66 | 62 | 45 | 39 | 93 | 102 |
Read_Max |  | R. aegyptiacus | Genome | 120 | 116 | 200 | 86 | 82 | 32 | 65 | 173 | 207 |
DESeq | | H. sapiens | Genome | 199.9 | 107.07 | 132.05 | 141.3 | 117.25 | 193.12 | 136.97 | 106.51 | 139.09 |
DESeq | | R. aegyptiacus | Transcriptome | 595.82 | 461.2 | 1121.15 | 530.26 | 605.49 | 307.68 | 443.74 | 562.82 | 656.16 |
DESeq | | R. aegyptiacus | Genome | 1511.67 | 1398.23 | 3003.67 | 1220.53 | 1673.08 | 774.11 | 1292.09 | 1588.27 | 1921.29 |