TGFB3

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TGFB3 ARVD1, RNHF, TGF-beta3 transforming growth factor, beta 3 NM_003239 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and is involved in embryogenesis and cell differentiation. Defects in this gene are a cause of familial arrhythmogenic right ventricular dysplasia 1.

The gene is very lowly but stably expressed in human cells. The bat cells homolog is morw highly expressed and shows downregulation in Ebola after 23 h and upregulation in Marburg after 23 h.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome20 6 12 10 10 15 10 13 8
Read_Max
batR. aegyptiacusTranscriptome 92 63 108 66 62 45 39 93 102
Read_Max
bat_genomeR. aegyptiacusGenome 120 116 200 86 82 32 65 173 207
DESeq
humanH. sapiensGenome 199.9 107.07 132.05 141.3 117.25 193.12 136.97 106.51 139.09
DESeq
batR. aegyptiacusTranscriptome 595.82 461.2 1121.15 530.26 605.49 307.68 443.74 562.82 656.16
DESeq
bat_genomeR. aegyptiacusGenome 1511.67 1398.23 3003.67 1220.53 1673.08 774.11 1292.09 1588.27 1921.29

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 199.9 141.3 136.97 -0.5 -0.55 -0.04
7h 107.07 117.25 106.51 0.13 -0.01 -0.14
23h 132.05 193.12 139.09 0.55 0.07 -0.47

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 199.9 107.07 132.05 -0.9 -0.6 0.3
Ebov 141.3 117.25 193.12 -0.27 0.45 0.72
Marv 136.97 106.51 139.09 -0.36 0.02 0.39

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 595.82 530.26 443.74 -0.17 -0.43 -0.26
7h 461.2 605.49 562.82 0.39 0.29 -0.11
23h 1121.15 307.68 656.16 -1.87 -0.77 1.09

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 595.82 461.2 1121.15 -0.37 0.91 1.28
Ebov 530.26 605.49 307.68 0.19 -0.79 -0.98
Marv 443.74 562.82 656.16 0.34 0.56 0.22