KIT

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
KIT PBT, SCFR,CD117, C-Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog pdf NONE NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

The gene KIT is not expressed in human cells datasets but moderately expressed in bat cells datasets. However, there are no significant changes in expression levels.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome1 0 0 0 0 2 0 0 0
Read_Max
batR. aegyptiacusTranscriptome 325 261 230 295 252 214 201 360 221
Read_Max
bat_genomeR. aegyptiacusGenome 365 309 190 260 189 121 168 385 239
DESeq
humanH. sapiensGenome 2.01 1.0 1.0 1.0 1.0 2.32 1.0 1.0 1.0
DESeq
batR. aegyptiacusTranscriptome 3690.06 3566.41 4160.33 4089.46 4327.7 3365.5 3584.06 4401.39 3275.03
DESeq
bat_genomeR. aegyptiacusGenome 4351.09 4613.62 4597.0 4530.57 5003.63 4005.0 4240.61 5013.0 3918.79

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2.01 1.0 1.0 -1.01 -1.01 0.0
7h 1.0 1.0 1.0 0.0 0.0 0.0
23h 1.0 2.32 1.0 1.21 0.0 -1.21

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2.01 1.0 1.0 -1.01 -1.01 0.0
Ebov 1.0 1.0 2.32 0.0 1.21 1.21
Marv 1.0 1.0 1.0 0.0 0.0 0.0

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3690.06 4089.46 3584.06 0.15 -0.04 -0.19
7h 3566.41 4327.7 4401.39 0.28 0.3 0.02
23h 4160.33 3365.5 3275.03 -0.31 -0.35 -0.04

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3690.06 3566.41 4160.33 -0.05 0.17 0.22
Ebov 4089.46 4327.7 3365.5 0.08 -0.28 -0.36
Marv 3584.06 4401.39 3275.03 0.3 -0.13 -0.43