KIT
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| KIT | PBT, SCFR,CD117, C-Kit | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |  |
NONE | NONE | NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
The gene KIT is not expressed in human cells datasets but moderately expressed in bat cells datasets. However, there are no significant changes in expression levels.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 |
Read_Max |  | R. aegyptiacus | Transcriptome | 325 | 261 | 230 | 295 | 252 | 214 | 201 | 360 | 221 |
Read_Max |  | R. aegyptiacus | Genome | 365 | 309 | 190 | 260 | 189 | 121 | 168 | 385 | 239 |
DESeq | | H. sapiens | Genome | 2.01 | 1.0 | 1.0 | 1.0 | 1.0 | 2.32 | 1.0 | 1.0 | 1.0 |
DESeq | | R. aegyptiacus | Transcriptome | 3690.06 | 3566.41 | 4160.33 | 4089.46 | 4327.7 | 3365.5 | 3584.06 | 4401.39 | 3275.03 |
DESeq | | R. aegyptiacus | Genome | 4351.09 | 4613.62 | 4597.0 | 4530.57 | 5003.63 | 4005.0 | 4240.61 | 5013.0 | 3918.79 |