RHOA

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RHOA ARH12, ARHA, RHO12, RHOH12,RhoA, Rho12 ras homolog family member A NM_001664 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion.

The gene expression level decreases after 7 h and is stable after 23 h in both control samples. After infection the gene expression levels change. Based on Ebola infection the expression level increases after 7 h and decreases after 23 h in human cells, in bat cells the expression level decreases after 7 h and increases after 23 h.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome2825 2024 1921 1983 2854 2549 2664 2659 2269
Read_Max
batR. aegyptiacusTranscriptome 1804 1678 1385 1446 1408 1667 1287 2109 2314
Read_Max
bat_genomeR. aegyptiacusGenome 2728 1774 1257 2176 1304 1069 1286 2647 2622
DESeq
humanH. sapiensGenome 19932.43 14480.14 12486.76 15869.04 14808.08 14813.02 15979.29 14564.37 16385.14
DESeq
batR. aegyptiacusTranscriptome 8133.56 8380.79 7939.77 7102.92 7625.02 8061.95 7201.6 8350.66 8941.4
DESeq
bat_genomeR. aegyptiacusGenome 14576.11 12125.02 11695.58 15565.7 12829.96 13417.0 12559.9 13078.85 13793.25

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 19932.43 15869.04 15979.29 -0.33 -0.32 0.01
7h 14480.14 14808.08 14564.37 0.03 0.01 -0.02
23h 12486.76 14813.02 16385.14 0.25 0.39 0.15

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 19932.43 14480.14 12486.76 -0.46 -0.67 -0.21
Ebov 15869.04 14808.08 14813.02 -0.1 -0.1 0.0
Marv 15979.29 14564.37 16385.14 -0.13 0.04 0.17

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 8133.56 7102.92 7201.6 -0.2 -0.18 0.02
7h 8380.79 7625.02 8350.66 -0.14 -0.01 0.13
23h 7939.77 8061.95 8941.4 0.02 0.17 0.15

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 8133.56 8380.79 7939.77 0.04 -0.03 -0.08
Ebov 7102.92 7625.02 8061.95 0.1 0.18 0.08
Marv 7201.6 8350.66 8941.4 0.21 0.31 0.1