SMAD3

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
SMAD3 HsT17436, JV15-2, MADH3,JV15-2, HsT17436 SMAD family member 3 NM_005902 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene `mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

It is constantly expressed in human cells and bat cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome146 132 113 164 152 177 201 164 136
Read_Max
batR. aegyptiacusTranscriptome 101 78 78 88 97 87 50 94 80
Read_Max
bat_genomeR. aegyptiacusGenome 109 85 75 75 82 52 44 103 110
DESeq
humanH. sapiensGenome 2811.96 2450.73 2719.35 2834.46 2430.1 3800.07 2857.18 2433.42 3995.91
DESeq
batR. aegyptiacusTranscriptome 460.56 404.01 605.66 519.27 539.78 559.18 305.8 490.12 489.96
DESeq
bat_genomeR. aegyptiacusGenome 766.58 837.84 1180.49 716.91 964.34 1013.0 640.98 873.83 1009.45

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2811.96 2834.46 2857.18 0.01 0.02 0.01
7h 2450.73 2430.1 2433.42 -0.01 -0.01 0.0
23h 2719.35 3800.07 3995.91 0.48 0.56 0.07

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2811.96 2450.73 2719.35 -0.2 -0.05 0.15
Ebov 2834.46 2430.1 3800.07 -0.22 0.42 0.65
Marv 2857.18 2433.42 3995.91 -0.23 0.48 0.72

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 460.56 519.27 305.8 0.17 -0.59 -0.76
7h 404.01 539.78 490.12 0.42 0.28 -0.14
23h 605.66 559.18 489.96 -0.12 -0.31 -0.19

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 460.56 404.01 605.66 -0.19 0.4 0.58
Ebov 519.27 539.78 559.18 0.06 0.11 0.05
Marv 305.8 490.12 489.96 0.68 0.68 -0.0