RAB11FIP1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RAB11FIP1 NOEL1A, RCP, rab11-FIP1,RCP, FLJ22622, FLJ22524, Rab11-FIP1 RAB11 family interacting protein 1 (class I) NM_025151 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants.

The gene is downregulated in human cells Ebola infected cells after 23 h. No homolog in bat cells was found.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome248 171 257 234 309 211 251 293 291
Read_Max
batR. aegyptiacusTranscriptome 56 52 22 40 38 24 30 48 56
Read_Max
bat_genomeR. aegyptiacusGenome 62 43 21 54 30 12 31 59 63
DESeq
humanH. sapiensGenome 6530.14 4181.46 5041.57 5239.02 4865.7 4165.89 5213.35 4175.21 7438.45
DESeq
batR. aegyptiacusTranscriptome 547.93 489.34 515.27 523.85 521.17 293.57 567.21 593.39 677.15
DESeq
bat_genomeR. aegyptiacusGenome 813.84 731.06 681.74 732.71 765.67 480.39 774.8 827.04 931.54

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 6530.14 5239.02 5213.35 -0.32 -0.32 -0.01
7h 4181.46 4865.7 4175.21 0.22 -0.0 -0.22
23h 5041.57 4165.89 7438.45 -0.28 0.56 0.84

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 6530.14 4181.46 5041.57 -0.64 -0.37 0.27
Ebov 5239.02 4865.7 4165.89 -0.11 -0.33 -0.22
Marv 5213.35 4175.21 7438.45 -0.32 0.51 0.83

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 547.93 523.85 567.21 -0.06 0.05 0.11
7h 489.34 521.17 593.39 0.09 0.28 0.19
23h 515.27 293.57 677.15 -0.81 0.39 1.21

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 547.93 489.34 515.27 -0.16 -0.09 0.07
Ebov 523.85 521.17 293.57 -0.01 -0.84 -0.83
Marv 567.21 593.39 677.15 0.07 0.26 0.19