MTOR

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
MTOR RAFT1, RAPT1, FLJ44809 mechanistic target of rapamycin (serine/threonine kinase) NM_004958 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene belongs to a family of phosphatidylinositolkinase-related kinases. These kinases mediate cellular responses to stressessuch as DNA damage and nutrient deprivation. This protein acts as the targetfor the cell-cycle arrest and immunosuppressive effects of theFKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of thisgene.

The gene is slightly expressed in all conditions. The is some evidence foralternative splicing in the bat cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome202 263 243 196 355 383 271 335 166
Read_Max
batR. aegyptiacusTranscriptome 204 196 127 156 155 171 135 169 176
Read_Max
bat_genomeR. aegyptiacusGenome 205 157 113 176 125 96 116 198 192
DESeq
humanH. sapiensGenome 7854.44 8891.23 7677.52 8278.94 8426.42 10940.26 8133.57 8605.21 6498.98
DESeq
batR. aegyptiacusTranscriptome 6108.82 5917.32 4826.07 5569.18 5890.39 5945.98 5382.82 5125.15 5105.8
DESeq
bat_genomeR. aegyptiacusGenome 6307.06 5708.84 4665.07 6470.98 6015.96 6202.0 5854.31 5075.65 5060.95

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7854.44 8278.94 8133.57 0.08 0.05 -0.03
7h 8891.23 8426.42 8605.21 -0.08 -0.05 0.03
23h 7677.52 10940.26 6498.98 0.51 -0.24 -0.75

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7854.44 8891.23 7677.52 0.18 -0.03 -0.21
Ebov 8278.94 8426.42 10940.26 0.03 0.4 0.38
Marv 8133.57 8605.21 6498.98 0.08 -0.32 -0.4

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 6108.82 5569.18 5382.82 -0.13 -0.18 -0.05
7h 5917.32 5890.39 5125.15 -0.01 -0.21 -0.2
23h 4826.07 5945.98 5105.8 0.3 0.08 -0.22

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 6108.82 5917.32 4826.07 -0.05 -0.34 -0.29
Ebov 5569.18 5890.39 5945.98 0.08 0.09 0.01
Marv 5382.82 5125.15 5105.8 -0.07 -0.08 -0.01