EIF3B

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
EIF3B PRT1, eIF3b eukaryotic translation initiation factor 3, subunit B pdf NONE

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Description

Homo sapiens eukaryotic translation initiation factor 3, subunit B (EIF3B), transcript variant 2, mRNA

The gene is equally strong expressed in all human cells samples. There is a good homolog hit in the bat cells transcriptome with slightly downregulation in the Ebola 7 h sample.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome1038 1298 1171 1232 1584 2031 1482 1721 1161
Read_Max
batR. aegyptiacusTranscriptome 496 346 212 293 286 330 416 366 339
Read_Max
bat_genomeR. aegyptiacusGenome 1335 723 463 1072 564 515 618 982 1078
DESeq
humanH. sapiensGenome 13979.69 15096.14 13869.77 15464.1 13894.33 22521.69 15793.32 16673.85 14345.28
DESeq
batR. aegyptiacusTranscriptome 2696.17 2400.02 1657.4 1916.58 2326.97 2610.99 2956.66 2085.52 2166.78
DESeq
bat_genomeR. aegyptiacusGenome 11151.45 8555.51 6863.15 11357.05 9973.77 10610.37 11337.53 8725.58 8870.15

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 13979.69 15464.1 15793.32 0.15 0.18 0.03
7h 15096.14 13894.33 16673.85 -0.12 0.14 0.26
23h 13869.77 22521.69 14345.28 0.7 0.05 -0.65

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 13979.69 15096.14 13869.77 0.11 -0.01 -0.12
Ebov 15464.1 13894.33 22521.69 -0.15 0.54 0.7
Marv 15793.32 16673.85 14345.28 0.08 -0.14 -0.22

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2696.17 1916.58 2956.66 -0.49 0.13 0.63
7h 2400.02 2326.97 2085.52 -0.04 -0.2 -0.16
23h 1657.4 2610.99 2166.78 0.66 0.39 -0.27

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2696.17 2400.02 1657.4 -0.17 -0.7 -0.53
Ebov 1916.58 2326.97 2610.99 0.28 0.45 0.17
Marv 2956.66 2085.52 2166.78 -0.5 -0.45 0.06