ARAP2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ARAP2 ArfGAP With RhoGAP Domain, Ankyrin Repeat And PH Domain 2, CENTD1, centaurin-delta,PARX ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 NM_015230 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

he protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. No detectable expression.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome6 0 6 2 2 2 2 0 1
Read_Max
batR. aegyptiacusTranscriptome 1 NA 2 NA NA 9 NA 1 3
Read_Max
bat_genomeR. aegyptiacusGenome 3 4 4 3 2 6 3 3 7
DESeq
humanH. sapiensGenome 1.0 1.0 1.0 2.14 1.0 8.9 2.75 1.0 4.26
DESeq
batR. aegyptiacusTranscriptome 2.68 1.0 3.44 1.0 1.0 15.11 1.0 2.65 9.75
DESeq
bat_genomeR. aegyptiacusGenome 17.19 13.69 13.39 12.84 5.58 80.94 14.62 13.48 58.22

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 2.14 2.75 1.1 1.46 0.36
7h 1.0 1.0 1.0 0.0 0.0 0.0
23h 1.0 8.9 4.26 3.15 2.09 -1.06

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 1.0 1.0 0.0 0.0 0.0
Ebov 2.14 1.0 8.9 -1.1 2.06 3.15
Marv 2.75 1.0 4.26 -1.46 0.63 2.09

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2.68 1.0 1.0 -1.42 -1.42 0.0
7h 1.0 1.0 2.65 0.0 1.41 1.41
23h 3.44 15.11 9.75 2.14 1.5 -0.63

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2.68 1.0 3.44 -1.42 0.36 1.78
Ebov 1.0 1.0 15.11 0.0 3.92 3.92
Marv 1.0 2.65 9.75 1.41 3.29 1.88