ITGA11

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ITGA11 ITGA11, HsT18964,HsT18964 integrin, alpha 11 NM_012211 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined.

ITGA11 is not expressed in human samples but it seems to be induced in bat MARV infected cells. This pattern is not shown in EBOV infected bat cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome5 7 4 2 6 16 10 9 16
Read_Max
batR. aegyptiacusTranscriptome 782 758 875 614 519 787 468 716 1113
Read_Max
bat_genomeR. aegyptiacusGenome 833 619 726 697 426 446 381 855 1198
DESeq
humanH. sapiensGenome 2.01 7.12 9.94 3.28 5.88 3.63 5.39 8.19 9.7
DESeq
batR. aegyptiacusTranscriptome 11066.49 12101.41 17416.45 9557.83 8894.23 12929.06 9305.16 8787.73 14888.54
DESeq
bat_genomeR. aegyptiacusGenome 12156.07 10406.43 18141.43 13989.68 9881.13 14713.28 10374.93 9160.9 16322.44

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2.01 3.28 5.39 0.71 1.42 0.72
7h 7.12 5.88 8.19 -0.28 0.2 0.48
23h 9.94 3.63 9.7 -1.45 -0.04 1.42

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2.01 7.12 9.94 1.82 2.31 0.48
Ebov 3.28 5.88 3.63 0.84 0.15 -0.7
Marv 5.39 8.19 9.7 0.6 0.85 0.24

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 11066.49 9557.83 9305.16 -0.21 -0.25 -0.04
7h 12101.41 8894.23 8787.73 -0.44 -0.46 -0.02
23h 17416.45 12929.06 14888.54 -0.43 -0.23 0.2

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 11066.49 12101.41 17416.45 0.13 0.65 0.53
Ebov 9557.83 8894.23 12929.06 -0.1 0.44 0.54
Marv 9305.16 8787.73 14888.54 -0.08 0.68 0.76