SOCS4

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
SOCS4 NM_080867, NP_955453, Q8WXH5, SOCS4_HUMAN, SOCS7 suppressor of cytokine signaling 4 pdf

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Description

he protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

There were no significant expression changes within these well-expressed gene.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome171 151 196 119 189 180 197 193 175
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 257 150 137 146 113 151 178 262 234
DESeq
humanH. sapiensGenome 3184.39 2813.81 3199.88 2396.43 2575.61 2824.97 2840.51 2474.19 3309.8
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 1690.42 1429.26 1184.96 1489.13 1333.78 1567.8 1885.84 1275.06 1196.96

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3184.39 2396.43 2840.51 -0.41 -0.16 0.25
7h 2813.81 2575.61 2474.19 -0.13 -0.19 -0.06
23h 3199.88 2824.97 3309.8 -0.18 0.05 0.23

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3184.39 2813.81 3199.88 -0.18 0.01 0.19
Ebov 2396.43 2575.61 2824.97 0.1 0.24 0.13
Marv 2840.51 2474.19 3309.8 -0.2 0.22 0.42

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA