ANAPC10
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| ANAPC10 | APC10, DOC1, DKFZP564L0562 | anaphase promoting complex subunit 10 | NM_014885 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940). The gene shows a slight down regulation in both, EBOV and MARV infected human cell samples 23h p.i..
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 32 | 29 | 31 | 32 | 30 | 31 | 38 | 49 | 23 |
Read_Max |  | R. aegyptiacus | Transcriptome | 52 | 43 | 58 | 29 | 35 | 37 | 29 | 45 | 48 |
Read_Max |  | R. aegyptiacus | Genome | 63 | 38 | 42 | 48 | 34 | 21 | 31 | 62 | 57 |
DESeq | | H. sapiens | Genome | 352.12 | 276.37 | 261.12 | 322.67 | 267.65 | 211.55 | 307.14 | 230.41 | 252.18 |
DESeq | | R. aegyptiacus | Transcriptome | 153.07 | 107.2 | 141.48 | 95.31 | 108.32 | 103.65 | 92.22 | 116.67 | 91.97 |
DESeq | | R. aegyptiacus | Genome | 495.01 | 434.44 | 384.94 | 368.33 | 371.67 | 270.22 | 475.68 | 428.98 | 342.48 |