Understanding the aging process is still a significant challenge to enable healthy aging and prevent age-related diseases. Most studies in age research investigate the decline in organ functionality and gene activity with age. The focus on decline can even be considered a paradigm in that field. However, certain aspects remain surprisingly stable and keep the organism robust.
We just have published a review article at Cells within the special issue “Aging and Regeneration”, were we present and discuss various properties of robust behavior during human and animal aging, including physiological and molecular biological features, such as the hematocrit, body temperature, immunity against infectious diseases, and others. We examine, in the context of robustness, the different theories of how aging occurs. We regard the role of aging in the light of evolution.